Implementation and Application of Computational Approaches to Integrate Generegulatory and Metabolic Networks
Implementierung und Anwendung rechengestützter Methoden zur Integration von genregulatorischen und metabolischen Netzwerken
- In this work a second version for the Python implementation of an algorithm called Probabilistic Regulation of Metabolism (PROM) was created and applied to the metabolic model iSynCJ816 for the organism Synechocystis sp. PCC 6803. A crossvalidation was performed to determine the minimal amount of expression data needed to produce meaningful results with the PROM algorithm. The failed reproduction of the results of a method called Integrated and Deduced Regulation of Metabolism (IDREAM) is documented and causes for the failed reproduction are discussed.
Download full text files
- Bachelorarbeit_Josua_Seidel.pdf
Additional Services
Statistics
| Author: | Josua Seidel |
|---|---|
| Advisor: | Röbbe Wünschiers, Nadine Töpfer |
| Document Type: | Bachelor Thesis |
| Language: | English |
| Year of Completion: | 2020 |
| Granting Institution: | Hochschule Mittweida |
| Release Date: | 2021/06/25 |
| GND Keyword: | Algorithmus; Mikroorganismus; Bioinformatik |
| Institutes: | Angewandte Computer‐ und Biowissenschaften |
| DDC classes: | 570.285 Bioinformatik |
| Open Access: | Innerhalb der Hochschule |
| Licence (German): |  Urheberrechtlich geschützt |
