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Investigating alternative therapeutic approaches for Erlotinib-resistant and K-Rras mutant non-small cell lung cancer

  • Different small molecule kinase inhibitors, which have an influence on cell growth, proliferation and cell survival were tested alone and in combination with Erlotinib in the Erlotinib-resistant non-small cell lung cancer cell line PC-9ER and Cisplatin in the K-Ras mutant cell line H358. The aim was to find out, which combinations produce the best antiproliferative effects in non-small cell lung cancer cell lines.

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Metadaten
Author:Kristin Uth
Document Type:Bachelor Thesis
Language:English
Year of Completion:2012
Granting Institution:Hochschule Mittweida, 03 Mathematik / Naturwissenschaften / Informatik
Release Date:2015/10/22
GND Keyword:Inhibitor , Rezeptor-Tyrosinkinasen , Epidermaler Wachstumsfaktor-Rezeptor , Lungenkrebs , Zelllinie
Institutes:03 Mathematik / Naturwissenschaften / Informatik
Access Rights:Innerhalb der Hochschule
Licence (German):License LogoEs gilt das UrhG

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