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Gold cyanidation is a process by which gold is removed from low-grade ore. Due to its efficiency it has found widespread application around the world, including Peru. The process requires free cyanide in high concentration. After the gold extraction is completed, free cyanide as well as metal cyanide complexes remain in the effluent of gold mines and refineries. Often these effluents are kept in storage ponds where they pose considerable risk to health and environ-ment. Thus, it is preferable to degrade cyanide to minimize the risk of exposure. In the context of this thesis cyanide degradation was explored in a UV-light based prototype. Degradation with a combination of hydrogen peroxide and UV-light has proven to be very effective at degrading cyanide concentrations of 100 mg/L and 1000 mg/L. Furthermore, the presence of ammonia as a degradation product could also be confirmed. Membrane distillation may provide an alternative to cyanide destruction in the form of cyanide recovery. Promising results were gathered from several membrane experiment.
Die biologische Ammoniumoxidation ist ein zentraler Bestandteil des globalen Stickstoffkreislaufs. Angesichts der extremen Massen Stickstoff anthropogenen Ursprungs in der Umwelt, liegt die Entfernung reaktiven Stickstoffs im Interesse der Umwelt und der öffentlichen Gesundheit. In der folgenden Arbeit werden Bedingungen zur anaeroben Ammoniumoxidation mit Nitrat in einem Anammox-Reaktor untersucht. Dabei wurden 2 Laborreaktoren für eine Zeit von insgesamt 116 Tagen betrieben und beobachtet, die ausschließlich als Elektronendonatoren und Akzeptoren Ammonium und Nitrat enthielten. Zusätzlich wurden Batchkulturen mit Zellen eines Reaktors angezüchtet und auf ihre Gaszusammensetzung abhängig unterschiedlicher Eigenschaften untersucht. Hierbei wurde eine Reihe unterschiedlicher analytischer Quantifizierungsmethoden genutzt und es konnte gezeigt werden, dass ein Abbau unter den Bedingungen stattfindet.
Die aktuelle Forschung zu dieser Reaktion ist spärlich und verleiht der Bachelorarbeit dadurch Relevanz.
In this thesis, we implement, correct, and modify the compartmental model described in “Transmission Dynamics of Large Coronavirus Disease Outbreak in Homeless Shelter, Chicago, Illinois, USA, 2020”. Our objective is to engage in reading and understanding scientific literature, reproduce the results, and modify or generalize an existing mathematical model. We provide an overview of epidemiological models, focusing on simple compartmental SEIR models. We correct inaccuracies and misprints in the original implementation and use the limited-memory Broyden–Fletcher–Goldfarb–Shanno algorithm to fit the model’s parameters. Furthermore, we modify the model by introducing an additional compartment. The resulting model has a more intuitive interpretation and relies on fewer assumptions. We also perform the fitting process for this alternative model. Finally, we demonstrate the advantages of our modified implementations and discuss other possible approaches.
In this work, we identify similarities between Adversarial Examples and Counterfactual Explanations, extend already stated differences from previous works to other fields of AI such as dimensionality, transferability etc. and try to observe these similarities and differences in different classifier with tabular and image data. We note that this topic is an open discussion and the work here isn’t definite and canbe further extended or modified in the future, if new discoveries found.
Footage of organoids taken by means of fluorescence microscopy and segmented as well as triangulated by image analysis software like LimeSeg and Mastodon often needs to be visualized in aesthetic manner for presentation of the results in scientific papers, talks and demonstrations. The goal of this work was to create a simple to use addon “Biobox” for the open source 3D – visualization package “Blender” which would allow to import triangulated 3D data with animation over time (4D), produced by image analysis software, and optimize it for efficient usage. ”Biobox” offers several visualization tools for the creation of rendered images and animation videos by biologists.
The optimization of imported data was performed by using Blender intern modifiers. The optimized data can then be visualized by using several tools built for visualizing the organoid in frozen, animated and semi-transparent manners. A dynamic link for object selection and dynamic data exchange between Blender and Mastodon was developed. Additionally, a user interface was developed for manual correction errors of segmentation and steering the object detection algorithms of LimeSeg. The benchmark of the developed addon “Biobox” was performed on real scientific data. The benchmark test demonstrated that developed optimization result in significant (~5 fold) decrease of RAM usage and acceleration of visualization more than 160 times.
This paper examines the communication channels used by innovation projects at the ProtoSpace Hamburg, when engaging with stakeholders, and tries to answer the thesis question whether new media channels improve the chances of success for innovation projects, when used for this communication. Expert interviews with eight experts in com-munication, innovation and stakeholder management were conducted and then analyzed through the application of Mayring´s qualitative content analysis, in order to answer the posed question.
The number of Internet of Things (IoT) devices is increasing rapidly. The Trustless Incentivized Remote Node Network, in short IN3 (Incubed), enables trustworthy and fast access to a blockchain for a large number of low-performance IoT devices. Although currently IN3 only supports the verification of Ethereum data, it is not limited to one blockchain due to modularity. This thesis describes the fundamentals, the concept and the implementation of the Bitcoin verification in IN3.
In this thesis two novel methods for removing undesired background illumination are de-veloped. These include a wavelet analysis based approach and an enhancement of a deep learning method. These methods have been compared with conventional methods, using real confocal microscopy images and synthetic generated microscopy images. These synthetic images were created utilizing a generator introduced in this thesis.
The Tutte polynomial is an important tool in graph theory. This paper provides an introduction to the two-variable polynomial using the spanning subgraph and rank-generating polynomials. The equivalency of definitions is shown in detail, as well as evaluations and derivatives. The properties and examples of the polynomial, i.e. the universality, coefficient relations, closed forms and recurrence relations are mentioned. Moreover, the thesis contains the connection between the dichromate and other significant polynomials.
The GeoFlow II experiment aims to replicate Earth’s core dynamics using a rotating spherical container with controlled temperature differences and simulated gravity. During the GeoFlow II campaign, a massive dataset of images was collected, necessitating an automated system for image processing and fluid flow visualization in the northern hemisphere of the spherical container. From here, we aim to detect the special structures appearing on the post processed images. Recognizing YOLOv5’s proficiency in object detection, we apply Yolov5 model for this task.
This study explores the opportunities and risks associated with user-generated content (UGC) in the communication strategies of marketing departments from a business perspective. With the rise of social media and online platforms, UGC has become a powerful tool for brands to engage with their audience, build trust, and enhance brand awareness. However, implementing UGC also comes with inherent risks, including the loss of control over brand messaging, potential negative user-generated content, and legal implications.
To investigate these dynamics, an empirical mixed-methods approach was employed, including expert interviews and a comprehensive literature review. The findings indicate that UGC offers significant opportunities for marketing departments, such as increased customer loyalty, enhanced authenticity, brand awareness, as well as a diverse set of possible content. However, the study also reveals the potential risks associated with UGC, highlighting the importance of managing these risks effectively.
The research of this thesis aims to analyze how a specific CSR approach from the Adidas Group on sustainability is perceived globally based on an analysis of the movements on the stock market combined with a sentiment analysis of tweet activities on Twitter. The thesis analyzed both positive feedback and critic from customers worldwide regarding the approach and other initiatives from the Adidas Group and their partner Parley for the Oceans, a non-governmental organization working towards a more sustainable world.
In the field of satellites it is common practice to combine multiple ground stations into one network, to increase communication times with satellites. This work focuses on TIM, which is an international academic colaborative project. Important criteria for this project are elaborated and used to evaluate existing ground station networks. It concludes that there is no appropriate solution availiable for this specific use case and establish a proposed solution. The proposed ground station network software will be elaborated and evaluated.
The games industry has significantly grown over the last 30 years. Projects are getting bigger and more expensive, making it essential to plan, structure and track them more efficiently.
The growth of projects has increased the administrative workload for producers, project managers and leads, as they have to monitor and control the progress of the project in order to keep a permanent overview of the project. This is often accompanied by a lack of insight into the project and basic communication within the team. Therefore, the goal of this thesis is to enhance conventional project management methods with process structures that occur frequently in game development.
This thesis initially elaborates on what project management in the game industry actually is: Here, methods are considered, especially agile methods and progress tracking prac-tices, which were created for software development and have become a standard in game development. Subsequently, an example is used to demonstrate how process management can function within the development of video games. Based on this, the ideal is depicted, which is implemented and used in a tool at the German games studio KING Art GmbH. This ideal is compared with expert interviews in order to verify its gen-eral validity in the industry.
By integrating process structures, the administrative effort can be reduced, communica-tion within game development can be simplified, while the current project status can be permanently presented. This benefits both project management and leads, as well as the entire team. Further application tests of this theory would have to be organized to check scalability and to draw comparisons to other applications.
Since its foundation as an application of algebra, coding theory is obtaining a day by day increasing importance. For instance, any communication system needs the concepts of coding theory to function efficiently. In this thesis, reader will find an introductory explanation to linear codes and binary hamming codes including some of the algebraic tools devised in their applications. All the described software applications are verified using SageMath 9.0 using Hochschule Mittweida’s JupyterHub.
In this work, a transgenic zebrafish line that expresses the fluorophore dsRed under the endogenous zebrafish cochlin promotor is supposed to be established, using the CRISPR/Cas9 system. dsRed was cloned into a pBluescript vector, followed by the cloning of the cochlin locus into this vector. This bait construct was then supposed to be micro injected into wild type AB zebrafish embryos. The micro injection of Cas9 mRNA, single guide RNA and a bait construct was practiced with the tyrosinase gene, which was disrupted using CRISPR/Cas9.
The objective of this Bachelor Project is the creation of a tool that should support forensic investigators during IT forensic interventions. It uses Kismet as the base program and adds functionalities to it via the plugin interface. The installation of the plugin shall be explained, how the plugin works, and a recommendation on how to use it. To understand the underlying basics, an introduction about WLAN and Bluetooth is given. The tests that were performed with the new plugin are described as well as their results. It is therefore briefly discussed why the tool is applicable for locating Wi-Fi devices, especially access points, but not Bluetooth devices. Using all this a few ideas on how to improve the tool and what can be researched in this area are provided.
This thesis aims to research the platform YouTube and whether “being a YouTuber” qualifies as a profession or not and what leads to this. The author combines existing scientific data and information provided by YouTubers doing this as a job and uses the compilation method. The author merges that material and uses it to create a bachelor thesis that covers both the theoretical and practical approach. The aim was to find out if there is a success recipe that can be followed that leads to views and clicks which are essential for the profession as a YouTuber. To do this, the author created two channels to see how the factors mentioned in this thesis are applied and if the approach leads to success. The findings of this thesis showed, that although the profession of a YouTuber can be classified as a job, it needs to be viewed differently from commonly known and in society accepted careers. Becoming a YouTuber and making money from this business, therefore, cannot be guaranteed.
The aim of this bachelor thesis is to find out how the use of artificial intelligence, specifically the one used in combat situations, can increase the playing time or even the replay value of games in the action role-playing genre. Thereby, it focuses mainly on combat situations between a player and an artificial intelligence.
To begin with, this bachelor thesis examines the action role-playing genre in order to find a suitable definition for it. Accordingly, action role-playing games involve titles that send the player on a hero’s journey-like adventure in which they must prove their skills in combat against virtual opponents. The greatest challenge of these real-time battles comes from the required quick reflexes, skill queries and hand-eye coordination.
Next, six means of increasing the replayability of a game are explored: Experience and Nostalgia, Variety and Randomness, Goals and Completion, Difficulty, Learning, and Social Aspect. The paper then proceeds to give an explanation for the term Artificial Intelligence and examines the various methods used to create intelligent behavior as well as the general advancement of the research field. Special attention is given to the implementation methods of Finite State Machines and Behavior Trees, as they are the most widely used methods for creating behavioral patterns of virtual characters.
Finally, a study conducted as part of the bachelor thesis is described, which compares a mathematically balanced artificial intelligence with a behaviorally balanced one in terms of game performance regarding the willingness of test subjects to purchase and play through the game as well as its replay value. The thesis concludes with the findings that while the behavioral approach is more promising than the mathematical approach, a combination of the two methods ultimately leads to the best outcome. Furthermore, the study shows that the use of artificial intelligence to individualize gaming experiences is promising for the future of the gaming industry.
Where does the cocoa, which we consume on a regular basis, come from? Supply chains are not always transparent, much less easily comprehensible. The cocoa industry faces ongoing challenges. Whether it be the chocolate manufacturers’ promise to maintain a sustainable and ethical supply chain, the minimal impact on the environment or the maximum adherence to human rights in their production process. This paper revises important steps which lead to the compliance with UN standards and questions the role of consumers in the construct of ethical chocolate products.
Studying and understanding the metabolism of plants is essential to better adapt them to future climate conditions. Computational models of plant metabolism can guide this process by providing a platform for fast and resource-saving in silico analyses. The reconstruction of these models can follow kinetic or stoichiometric approaches with Flux Balance Analysis being one of the most common one for stoichiometric models. Advances in metabolic modelling over the years include the increasing number of compartments, the automation of the reconstruction process, the modelling of plant-environment interactions and genetic variants or temporally and spatially resolved models. In addition, there is a growing focus on introducing synthetic pathways in plants to increase their agricultural potential regarding yield, growth and nutritional value. One example is the β-hydroxyaspartate cycle (BHAC) to bypass photorespiration. After the implementation in a stoichiometric C3 plant model, in silico flux analyses can help to understand the resulting metabolic changes. When comparing with in vivo experiments with BHAC plants, the metabolic model can reproduce most results with exceptions regarding growth and oxaloacetate. To evaluate whether the BHAC is suitable to establish a synthetic C4 cycle, the pathway is implemented in a two-cell type model that is capable of running a C4 cycle. The results show that the BHAC is only beneficial under light limitation in the bundle sheath cell. An additional engineering target for improved performance of plants is malate synthase. This work serves as the basis for further analyses combining the different factors boosting the advantages of the BHAC and for in vivo experiments in C3 and C4 plants.
This Bachelor thesis investigates the learning rules of the Hebbian, Oja and BCM neuron models for their convergence to, and the stability of, the fixed points. Existing research is presented in a structured manner using consistent notation. Hebbian learning is neither convergent nor stable. Oja learning converges to a stable fixed point, which is the eigenvector corresponding to the largest eigenvalue of the covariance matrix of the input data. BCM learning converges to a fixed point which is stable, when assuming a discrete distribution of orthogonal inputs that occur with equal probability. Hebbian learning can therefore not be used in further applications, where convergence to a stable fixed point is required. Furthermore, this Bachelor thesis came to the conclusion that determining the fixed points of the BCM learning rule explicitly involves extensive calculation and other methods for verifying the stability of possible fixed points should be considered.
Simulating complex physical systems involves solving nonlinear partial differential equations (PDEs), which can be very expensive. Generative Adversarial Networks (GAN) has recently been used to generate solutions to PDEs-governed complex systems without having to numerically solve them.
However, concerns are raised that the standard GAN system cannot capture some important physical and statistical properties of a complex PDE-governed system, along side with other concerns for difficult and unstable training, the noisy appearance of generated samples and lack of robust assessment methods of the sample quality apart from visual examination. In this thesis, a standard GAN system is trained on a data set of Heat transfer images. We show that the generated data set can capture the true distribution of training data with respect to both visual and statistical properties, specifically the vertical statistical profile. Furthermore, we construct a GAN model which can be conditioned using variance-induced class label. We show that the variance threshold t = 0. 01 constructs a good conditional class label, such that the generated images achieve 96% accuracy
rate in complying with the given conditions.
Tokenization projects are currently very present when it comes to new blockchain technologies. After explaining the fundamentals of cross-chain interaction, the bachelor thesis will focus on tokenizing technology for Bitcoin on Ethereum. To get a more practical context, implementing the currently most successful decentralized tokenization project is described.
In the following bachelor thesis the current trends and potential applications of digitalization in the service industry will be discussed. With the nowadays surging demand on digitalization in all industries, there are branches of the service industry where digitalization is yet to be exploited to its full potential. However, it is difficult to pick and choose which branches of the industry should be fully digitized and which should be partially digitized. The result of this work should therefore facilitate the process of applying digitization in the consulting services where face to face human interaction has been the key to the industry for years. For this purpose, essential factors to be taken into account were identified, which are to be sought after through the analysis, in the specification of the system requirements as well as in the performance of a utility value analysis.
In dieser Arbeit wurden neuartige Proteasen aus psychrotoleranten Bakterienstämmen isoliert und auf ihre biochemischen Eigenschaften charakterisiert. Des Weiteren konnten S8 Familie Proteasen Gene amplifiziert werden und Unterschiede in der Aminosäuresequenz konnten in Zusammenhang mit den biochemischen Eigenschaften der Proteasen in Verbindung gebracht werden.
In an era of global climate change and fast growing cities, local governments are in an urgent need for adopting sustainable urban growth concepts for tackling a liveable and prosperous urban future. Against this background, the smart city notion progressively gained popularity as an urban development concept, which heavily relies on technology and urban data use for fostering sustainable urban growth. However, so far, the understandingof the smart city term is ambiguous, and little scientific research has been done on developing comprehensive conceptual frameworks to support local governments in the making of smarter cities. This paper aims at presenting the current state-of-the-art of smart city research in order to support the making of smart city best practices and to promote a comprehensive understanding of the smart city notion. In doing so, the role of technology in the making of smarter cities and critical success factors in transforming cities are elaborated, following the methodological approach of a multidimensional conceptual framework. The research findings and an expert interview with a representative of the state capital will then serve for the assessment of the weak points and best practices in the smart city pursuit of the German city Munich, providing urban policymaking with valuable insights and fostering the development of a comprehensive smart city conceptualism.
In this work a second version for the Python implementation of an algorithm called Probabilistic Regulation of Metabolism (PROM) was created and applied to the metabolic model iSynCJ816 for the organism Synechocystis sp. PCC 6803. A crossvalidation was performed to determine the minimal amount of expression data needed to produce meaningful results with the PROM algorithm. The failed reproduction of the results of a method called Integrated and Deduced Regulation of Metabolism (IDREAM) is documented and causes for the failed reproduction are discussed.
This thesis provides an overview of Generation Z with a focus on Mittweida University of Applied Sciences students. It explores the general issues of students' behavior in life, as well as their attitudes toward the financial and banking sectors. It also examines the German banking market, its strengths and weaknesses in attracting new clients. At the end, possible strategies for the development of the bank in terms of attractiveness for young people are provided.
The bachelor thesis is assigned to introduce the theoretical concept of Human Recourses Management, to analyze the work of human resources department of the LLC Tavria-V and to offer actions with recommendation to improve the productivity of the personnel. To start the implementation of actions for personnel management improvement, first of all, an overview of theoretical and methodological aspects of the HRM are presented and theories which earlier had an impact on our present running of the "workers" are described. Secondly, the concept of organizational work of the enterprise, main indexes and types of activities are figured out and in the form of tables and diagrams analyzed. The main object of the thesis - the process of personnel management with qualitative characteristics is described and presented. Using also the survey of employee all advantages and disadvantages of the present system of HRM are defined. Then in the last part, taking to account all data about current situation, recommended actions and effect for LLC Tavria-V on the basis of the personnel management analysis are presented in the work.
In this thesis, the changes in economy and society and the resulting effects on the labor market are being outlined. Current studies show that the shrinking labor market and the increasing digitalization result in a lack of skilled tech talent and a transition from an employer market to a clear employee market. Derived from the findings of the scientific research on this topic and conducted expert interviews, practical recommendations for recruitment actions within the scope of employer branding will be defined in order to help corporations to gain the needed tech skill set and drive innovation.
The epithelial membrane proteins (EMP1-3), which belong to the family of peripheral myelin proteins 22-kDa (PMP22), are involved in epithelial differentiation. EMP2 was found to be a downstream target gene of the tumor suppressor gene HOPX, a homeobox-containing gene. Additionally, a dysregulation of EMP2 has been observed in various cancers, but the function of EMP2 in human lung cancer has not yet been clarified.
In this study, a real-time RT-PCR, Western blot and cytoblock analysis were performed to analyze the expression of EMP2. Gain-of-function was achieved by stable transfection with an EMP2 expression vector and loss-of-function by siRNA knockdown. Stable transfection led to overexpression of EMP2 at both mRNA and protein levels in the transfected cell lines H1299 and H2170.
Functional assays including proliferation, colony formation, migration and invasion assays as well as cell cycle analyzes were performed after stable transfection and it was found that the ectopic EMP2 expression resulted in a reduced cell proliferation, migration and invasion as well as a G1 cell cycle arrest. After the EMP2 gene was silenced by the siRNA knockdown, inhibition of the cell invasive property was observed. These phenomena were accompanied by reduced AKT, mTor and p38 activities.
Taken together, the data suggest that the epithelial membrane protein 2 (EMP2) is a tumor suppressor and exerts its tumor suppressive function by inhibiting AKT and MAPK signaling pathways in human lung cancer cells.
The aim of this bachelor thesis was to establish extracytoplasmic function (ECF) σ factors as synthetic genetic regulators for biotechnological and synthetic biology applications in the new emerging model organism Vibrio natriegens. Therefore, synthetic genetic circuits were engineered on plasmids as test set-up for the investigated ECFs and their target promoters. The resulting plasmid library consisted of the reporter plasmids with the target promoter, fused to a lux cassette, a set of high-copy ECF plasmids and a backup set of lower-copy ECF plasmids. First, the high-copy plasmids were transformed in V. natriegens to test them for their functionality upon different inducer levels, which yielded good inducibility for few, but showed too high ECF-expression in most strains. For this reason, the set of lower copy plasmids was used for combinatorial co-transformation, to investigate the ECFs for their cross-talk to unspecific ECF target promoters. The switching to the lower-copy plasmid-set seemed to be partly helpful, while still much room for fine-tuning of the circuits remains. The knowledge gained can be used to achieve higher success rates when engineering synthetic circuits for various applications in V. natriegens, by using the ECFs here recommended as suitable synthetic genetic regulators.
Workload Optimization Techniques for Password
Guessing Algorithms on Distributed Computing Platforms
(2019)
The following thesis covers several ways to optimize distributed computing platforms for cryptanalytic purposes. After an introduction on password storage, password guessing attacks and distributed computing in general, a set of inital benchmark results for a variety of different devices will be analyzed. The shown results are mainly based on utilization of the open source password recovery tool Hashcat. The second part of this work shows an algorithmic implementation for information retrieval and workload generation. This thesis can be used for the conception of a distributed computing system, inventory analysis of available hardware devices, runtime and cost estimations for specific jobs and finally strategic workload distribution.
In the present bachelor thesis, nanopore sequencing and Illumina sequencing was compared using pollen DNA collected from honeybees and bumble bees. Therefore, nanopore sequencing was performed with the MinION sequencers and the generated reads were analysed with bash programming. A quantitative and qualitative (based on ITS2 sequences) BLAST run was performed. The results confirme the error probability of nanopore sequencing that is described in the literature. Nevertheless, with both sequencing methods similar sample preferences of the bees could have been observed, allowing ecological conclusions.
This thesis deals with the development of a methodology / concept to analyse targeted attacks against IIoT / IoT devices. Building on the established background knowledge about honeypots, fileless malware and injection techniques a methodology is created that leads to a concept of a honeypot analyzation system. The system is created to analyse and detect novel threats like fileless attacks which are often utilized by Advanced Persistent Threats. That system is partially implemented and later evaluated by performing a simulated attack utilizing fileless attacks. The effectiveness is discussed and rated based on the results.
The subject of the following paper is the analysis of global company motives for taking on sport sponsorships as a corporate social responsibility (CSR) initiative. This work is compilatory in nature because it is derived from literature released by experts as well as real-life case studies. The expert literature provides a basis of theories and models regarding the fundamental motives for CSR and sport sponsoring and visualizes them by means of statistics and real-life case studies. This paper aims to inform individuals, leaders and specifically global organizations about the benefits that taking on a sport sponsorship may have for fulfilling a company’s CSR objectives
Aminoacyl-tRNA synthetases (aaRSs) are key enzymes in the process of protein biosynthesis, charging tRNA molecules with their corresponding amino acid. Whereas adenosine phosphate fixation is common to all aaRSs, recognition of the respective amino acid to ensure correct translation poses a complex task, which is still not understood to its full extent. Using all aaRS structures in the Protein Data Bank (PDB), this thesis reveals further details about the specificitydetermining interactions of each aaRS. Moreover, inspection of the similarities between these enzymes using the structure-derived interaction data reinforces the sequence-based evolutionary trace of aaRSs to a certain degree: The concurrent development of two distinct Classes of aaRS is apparent at functional level, and previously determined evolutionary subclasses coincide altogether with specific aminoacyl recognition in each aaRS Type. Still, discrimination of amino acids in aaRSs involves a multitude of further relevant mechanisms. Eventually, analysis of specificity-relevant binding site interactions sheds light on how aaRS evolved to distinguish different amino acids.
In the following study the properties of the superabsorbent polymer Broadleaf P4 were investigated according to the aim to apply that polymer within constructed wetlands. The application of the polymer in constructed wetlands shall result in an improvement of the removal of pesticides. For that the polymer was given into lab-scale wetlands together with pumice and were compared to a control wetland, which was filled with gravel. The wetlands were running for several weeks in which the nutrient removal was recorded. The polymer was also tested according to its property to adsorb the pesticides before adding the pesticides to the wetland beds.
Social media platforms play an increasing role in marketing, politics and police affairs, because they can strongly influence opinions. So called “opinion leaders” exert their influence in a given network and shape the opinions of other users. Identifying central nodes in a social graph has been of interest for decades. However, not all centrality measures were developed for social media platforms. They were built for social graphs, which did not include additional metrics (e.g. “likes”, “shares”). Nevertheless, these metrics play a crucial role on modern platforms. Hence, outdated measures need to be adjusted and additional metrics need to be integrated to ensure the best possible results.
In this work, the task is to cluster microarray gene expression data of the cyanobacterium Nostoc PCC 7120 for detection of messenger RNA (mRNA) degradation patterns. Searched are characteristic patterns of degradation which are caused by specific enzymes (ribonucleases) allowing a further biological investigation regarding biochemical mechanisms. The mRNA degradation is part of the regulation of gene expression because it regulates the amount and longevity of mRNA, which is available for translation into proteins. A particular class of RNA degrading enzymes are exoribonucleases which degrade the molecule from its ends, whereby a degradation from the 5’ end, the 3’ end or from both ends is theoretically possible.
In this investigation, the information about exoribonucleolytic degradation is given in a microarray data set containing gene expression values of 1,251 genes. The data set provides gene expression vectors containing the expression values of up to ten short distinct sections of a gene ordered from the genes 5’ end to its 3’ end. For each gene, expression vectors are available for both nitrogen fixing and non-nitrogen fixing conditions, which have to be considered separately due to biological reasons. Accordingly, after filtering and preprocessing, two datasets for clustering are obtained consisting of 133 ten-dimensional expression vectors. The similarity of the expression vectors is judged by a newly correlation based similarity measure and compared with the results obtained by use of the Euclidean distance. A non-linear transformation of the correlations was applied to obtain a dissimilarity measure. By choice of parameters within this transformation a user specific differentiation between negative and positive correlated gene expression vectors and an adequate adjustment regarding the noise level of gene expression values is possible.
Clustering was performed using Affinity Propagation (AP). The number of clusters obtained by AP depends on the so-called self-similarity for the data vectors. This dependence was used to identify stable cluster solutions by self-similarity control. To evaluate the clustering results, Median Fuzzy c-Means (M-FCM) was used. Further, several cluster validity measures are applied and visual inspections by t-distributed Stochastic Neighbor Embedding (t-SNE) as well as cluster visualization are provided for mathematical interpretation analysis of clusters.
To validate the clustering results biologically, the found data structure is checked for biological adequacy. A deeper investigation into the mechanisms behind mRNA-degradation was achieved by use of a RNA-Seq data set. Contained 40 (base pair) bp long reads for non-nitrogen fixing and nitrogen fixing conditions were assembled using bacteria-specific ab-initio assembly of Rockhopper. Thus, mRNA (transcript)-sequences of the clustered genes are obtained. A further investigation of the untranslated regions (UTRs) is performed here due to the assumption that exoribonucleases recognize specific transcript-sequences outside of the annotated gene regions as their binding sites. These UTRs need to be analyzed regarding sequence similarity using motif-finding algorithms.
In the context of globalization and the internationalization of international markets, mergers and acquisitions are becoming increasingly important for transnational corporations and national economies of countries as a form of internationalization, integration and the way to attract foreign investment. In the framework of this paper, the theoretical aspects of mergers and acquisitions have been analyzed, and the experience of Germany, China and Russia in attracting investments through mergers and acquisitions has been examined, and the success of this method for each country has been assessed.
DropConnect (the generalization of Dropout) is a very simple regularization technique that was introduced a few years ago and has become extremely popular because of its simplicity and effectiveness. In this thesis, a suitable architecture for applying DropConnect to Learning Vector Quantization networks is proposed along with a reference implementation and experimental results. Inmany classification tasks, the uncertainty of themodel is a vital piece of information for experts. Methods to extract the uncertainty and stability using DropConnect are also proposed and the corresponding experimental results are documented.
Abstract nicht vorhanden
The following is a description and outline of the work done at the Cornell Lab of Ornithology developing Nation Feathers VR, a virtual reality game for learning about bird calls and songs. The goal was to develop a game which is intuitive, educational and entertaining. Furthermore, the software needed to be structured in a way that allows for feasible future expansion. This required careful data saving and retrieval. The game gives the player an opportunity to learn and apply that knowledge, all while maintaining a shorter runtime in order to reduce the total time spent in the virtual world. This is meant to prevent any discomfort to the player that may result from extended use of the VR headset.
In this work, we discuss the key role that “conflict minerals” (Gold, Coltan, Cobalt, Tin, Tungsten) play in global supply chains and high-technology industries, and the issues surrounding their extraction and trade in origin
countries, particularly in the African Congo Basin and the Great Lakes Region. We discuss ongoing international efforts to combat violence, child labour and human rights violations at mineral extraction areas, particularly in the Democratic Republic of the Congo (DRC), where very large mineral reserves have been discovered. We present the OECD Due Diligence Guidance for Responsible Supply Chains of Minerals from Conflict-Affected and High-Risk Areas, and the
GOTS MineralTrace mineral proof-of-origin and trade chain certification solution developed by ibes AG in Germany, which automates and simplifies the implementation of the OECD Guidance. We discuss a pilot project in DRC involving the GOTS GoldTrace application, based on the MineralTrace platform. We point out MineralTrace’s benefits and its limitations. We analyse possible solutions to said limitations, including an analysis of blockchain-based transactional information exchange and record keeping systems, and finally we propose a new MineralTrace Application Programming Interface (API) that solves current limitations, introduces configuration flexibility for client applications, introduces workflow flexibility to adapt MineralTrace to any country or region, and simplifies data export functionality.
Object detection and classification is active field of research inmachine learning and computervision. Depending on the application there are different limitations to adjust to, but also possibilities to take advantage of. In my thesis, We focus on classification and detection of video sequence during night-time and the proposed method is robust since it does use image thresholding [8] which is commonly use in other methods and the thesis uses histograms of oriented gradients (HOG) [37] as features and support vector machine (SVM) [74] as classifier. It is of great importance that the extracted features from the images should be robust and distinct enough to help the classifier distinguish between high-beam and a low-beam. The classifier is part of the object detection which predicts whether or not a testing image matches one group or the other. In our case that is predicting whether or not an image belongs to high or low-beam sequence.
Success story DAB in the UK
(2017)
The popularity of digital audio broadcasting in different countries can be explained mainly by means of historical development. In this work, the general technical conditions are explained and the mode of operation is explained. In addition, advantages, disadvantages and alternatives are presented. After that, the development of the digital radio in Germany and the UK is compared with the current situation in order to show how the differences have led to a different distribution and acceptance of the medium.