Investigating alternative therapeutic approaches for Erlotinib-resistant and K-Rras mutant non-small cell lung cancer
- Different small molecule kinase inhibitors, which have an influence on cell growth, proliferation and cell survival were tested alone and in combination with Erlotinib in the Erlotinib-resistant non-small cell lung cancer cell line PC-9ER and Cisplatin in the K-Ras mutant cell line H358. The aim was to find out, which combinations produce the best antiproliferative effects in non-small cell lung cancer cell lines.
Author: | Kristin Uth |
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Document Type: | Bachelor Thesis |
Language: | English |
Year of Completion: | 2012 |
Granting Institution: | Hochschule Mittweida, 03 Mathematik / Naturwissenschaften / Informatik |
Release Date: | 2015/10/22 |
GND Keyword: | Inhibitor , Rezeptor-Tyrosinkinasen , Epidermaler Wachstumsfaktor-Rezeptor , Lungenkrebs , Zelllinie |
Institutes: | 03 Mathematik / Naturwissenschaften / Informatik |
DDC classes: | 615 Pharmakologie, Therapeutik |
Open Access: | Innerhalb der Hochschule |
Licence (German): | Urheberrechtlich geschützt |